ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2019, Vol. 50 ›› Issue (9): 1737-1745.doi: 10.11843/j.issn.0366-6964.2019.09.002
• REVIEW • Previous Articles Next Articles
HU Wenping1, TANG Jishun1,2, ZHANG Zhuangbiao1, LA Yongfu1, LIU Qiuyue1, DI Ran1, WANG Xiangyu1, CHU Mingxing1*
Received:2019-02-28
Online:2019-09-23
Published:2019-09-23
CLC Number:
HU Wenping, TANG Jishun, ZHANG Zhuangbiao, LA Yongfu, LIU Qiuyue, DI Ran, WANG Xiangyu, CHU Mingxing. Progress of Izumo1 and Juno in Mammalian Fertilization[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(9): 1737-1745.
| [1] INOUE N,IKAWA M,ISOTANI A,et al.The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs[J].Nature,2005,434(7030):234-238. [2] BIANCHI E,DOE B,GOULDING D,et al.Juno is the egg Izumo receptor and is essential for mammalian fertilization[J]. Nature, 2014,508(7497):483-487. [3] WASSARMAN P M.Reproductive biology:sperm protein finds its mate[J].Nature,2014,508(7497):466-467. [4] STEIN K K,PRIMAKOFF P,MYLES D.Sperm-egg fusion:events at the plasma membrane[J].J Cell Sci,2004,117(26):6269-6274. [5] CUASNICÚ P S,DA ROS V G,WEIGEL MUÑOZ M,et al.Acrosome reaction as a preparation for gamete fusion[M]//BUFFONE M G.Sperm Acrosome Biogenesis and Function During Fertilization.Cham:Springer,2016:159-172. [6] BLEIL J D,WASSARMAN P M.Mammalian sperm-egg interaction:identification of a glycoprotein in mouse egg zonae pellucidae possessing receptor activity for sperm[J].Cell,1980,20(3):873-882. [7] GANGULY A,BUKOVSKY A,SHARMA R K,et al.In humans,zona pellucida glycoprotein-1 binds to spermatozoa and induces acrosomal exocytosis[J].Hum Reprod,2010,25(7):1643-1656. [8] GAHLAY G,GAUTHIER L,BAIBAKOV B,et al.Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein[J].Science,2010,329(5988):216-219. [9] KLINOVSKA K,SEBKOVA N,DVORAKOVA-HORTOVA K.Sperm-egg fusion:a molecular enigma of mammalian reproduction[J]. Int J Mol Sci,2014,15(6):10652-10668. [10] BIANCHI E,WRIGHT G J.Cross-species fertilization:the hamster egg receptor,Juno,binds the human sperm ligand, Izumo1[J]. Philos Trans Roy Soc Lond B Biol Sci,2015,370(1661):20140101. [11] BLOBEL C P,WOLFSBERG T G,TURCK C W,et al.A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion[J].Nature,1992,356(6366):248-252. [12] ZHU X L,BANSAL N P,EVANS J P.Identification of key functional amino acids of the mouse fertilin β (ADAM2) disintegrin loop for cell-cell adhesion during fertilization[J].J Biol Chem,2000,275(11):7677-7683. [13] CHO C,BUNCH D O,FAURE J E,et al.Fertilization defects in sperm from mice lacking fertilin β[J].Science, 1998, 281(5384):1857-1859. [14] INOUE N.Novel insights into the molecular mechanism of sperm-egg fusion via IZUMO1[J].J Plant Res,2017,130(3):475-478. [15] DORFMAN R,SHILO B Z.Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region[J].Development,2001,128(6):965-972. [16] OKABE M.The cell biology of mammalian fertilization[J].Development,2013,140(22):4471-4479. [17] GARDNER A J,EVANS J P.Mammalian membrane block to polyspermy:new insights into how mammalian eggs prevent fertilisation by multiple sperm[J].Reprod Fertil Dev,2006,18(1-2):53-61. [18] IKAWA M,INOUE N,BENHAM A M,et al.Fertilization:a sperm's journey to and interaction with the oocyte[J].J Clin Invest, 2010,120(4):984-994. [19] LE NAOUR F,RUBINSTEIN E,JASMIN C,et al.Severely reduced female fertility in CD9-deficient mice[J].Science, 2000,287(5451):319-321. [20] MIYADO K,YAMADA G,YAMADA S,et al.Requirement of CD9 on the egg plasma membrane for fertilization[J]. Science,2000,287(5451):321-324. [21] KAJI K,ODA S,SHIKANO T,et al.The gamete fusion process is defective in eggs of Cd9-deficient mice[J].Nat Genet, 2000,24(3):279-282. [22] CLAW K G,GEORGE R D,SWANSON W J.Detecting coevolution in mammalian sperm-egg fusion proteins[J].Mol Reprod Dev, 2014,81(6):531-538. [23] BIANCHI E,WRIGHT G J.Izumo meets Juno:preventing polyspermy in fertilization[J].Cell Cycle,2014,13(13):2019-2020. [24] ALFIERI J A,MARTIN A D,TAKEDA J,et al.Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins[J].J Cell Sci,2003,116(11):2149-2155. [25] COONROD S A,NAABY-HANSEN S,SHETTY J,et al.Treatment of mouse oocytes with PI-PLC releases 70-kDa (pI 5) and 35-to 45-kDa (pI 5.5) protein clusters from the egg surface and inhibits sperm-oolemma binding and fusion[J].Dev Biol, 1999, 207(2):334-349. [26] WRIGHT G J.Signal initiation in biological systems:the properties and detection of transient extracellular protein interactions[J]. Mol BioSyst,2009,5(12):1405-1412. [27] YAMAGUCHI T,HIROTA K,NAGAHAMA K,et al.Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor[J].Immunity,2007,27(1):145-159. [28] TENG M W L,SWANN J B,VON SCHEIDT B,et al.Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion[J].Cancer Res,2010,70(7):2665-2674. [29] LIANG S C,MOSKALENKO M,VAN ROEY M,et al.Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy[J].Clin Immunol,2013,148(2):287-298. [30] KINOSHITA M,KAYAMA H,KUSU T,et al.Dietary folic acid promotes survival of Foxp3+ regulatory T cells in the colon[J].J Immunol,2012,189(6):2869-2878. [31] SALBAUM J M,KRUGER C,KAPPEN C.Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation[J].Biochim Biophys Acta,2013,1832(10):1653-1661. [32] CHEN C,KE J Y,ZHOU X E,et al.Structural basis for molecular recognition of folic acid by folate receptors[J]. Nature, 2013, 500(7463):486-489. [33] WIBOWO A S,SINGH M,REEDER K M,et al.Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition[J].Proc Natl Acad Sci U S A,2013,110(38):15180-15188. [34] GRAYSON P,CIVETTA A.Positive selection and the evolution of izumo genes in mammals[J].Int J Evol Biol,2012,2012:958164. [35] KIM E,KIM J S,LEE Y,et al.Molecular cloning,characterization of porcine IZUMO1,an IgSF family member[J].Reprod Domest Anim,2013,48(1):90-97. [36] ELLERMAN D A,PEI J M,GUPTA S,et al.Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm[J].Mol Reprod Dev,2009,76(12):1188-1199. [37] AYDIN H,SULTANA A,LI S,et al.Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex[J]. Nature,2016,534(7608):562-565. [38] XING W J,HAN B D,WU Q,et al.Molecular cloning and characterization of Izumo1 gene from sheep and cashmere goat reveal alternative splicing[J].Mol Biol Rep,2011,38(3):1995-2006. [39] OHTO U,ISHIDA H,KRAYUKHINA E,et al.Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization[J].Nature,2016,534(7608):566-569. [40] KRAUCHUNAS A R,SINGSON A.Marriage shrines and worms impacting our understanding of mammalian fertilization[J]. Worm,2016,5(3):e1184389. [41] JEAN C,HAGHIGHIRAD F,ZHU Y,et al.JUNO,the receptor of sperm IZUMO1,is expressed by the human oocyte and is essential for human fertilisation[J].Hum Reprod,2019,34(1):118-126. [42] SUZUKI B,SUGANO Y,ITO J,et al.Location and expression of Juno in mice oocytes during maturation[J].JBRA Assist Reprod, 2017,21(4):321-326. [43] DAI X X,LU Y J,ZHANG M Q,et al.Melatonin improves the fertilization ability of post-ovulatory aged mouse oocytes by stabilizing ovastacin and Juno to promote sperm binding and fusion[J].Hum Reprod,2017,32(3):598-606. [44] YOUNG S A M,MIYATA H,SATOUH Y,et al.CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility[J].Reproduction,2016,152(6):665-672. [45] CHALBI M,BARRAUD-LANGE V,RAVAUX B,et al.Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilization[J]. Development, 2014, 141(19):3732-3739. [46] YU M R,ZHAO H,CHEN T L,et al.Mutational analysis of IZUMO1R in women with fertilization failure and polyspermy after in vitro fertilization[J].J Assist Reprod Genet,2018,35(3):539-544. [47] NISHIMURA H,L'HERNAULT S W.Gamete interactions require transmembranous immunoglobulin-like proteins with conserved roles during evolution[J].Worm,2016,5(3):e1197485. [48] ZHOU C,HUANG L,SHI D S,et al.Effects of latrunculin A on the relocation of sperm IZUMO1 during gamete interaction in mouse[J]. Mol Reprod Dev,2017,84(11):1183-1190. [49] FUKUDA M,SAKASE M,FUKUSHIMA M,et al.Changes of IZUMO1 in bull spermatozoa during the maturation,acrosome reaction,and cryopreservation[J].Theriogenology,2016,86(9):2179-2188. [50] INOUE N,HAGIHARA Y,WRIGHT D,et al.Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice[J].Nat Commun,2015,6:8858. [51] INOUE N,WADA I.Monitoring dimeric status of IZUMO1 during the acrosome reaction in living spermatozoon[J].Cell Cycle,2018,17(11):1279-1285. [52] MELCHER K.Structural biology:when sperm meets egg[J].Nature,2016,534(7608):484-485. [53] INOUE N,HAMADA D,KAMIKUBO H,et al.Molecular dissection of IZUMO1,a sperm protein essential for sperm-egg fusion[J]. Development,2013,140(15):3221-3229. [54] LORENZETTI D,POIRIER C,ZHAO M,et al.A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion[J].Mamm Genome,2014,25(3-4):141-148. [55] FROLIKOVA M,MANASKOVA-POSTLEROVA P,CERNY J,et al.CD9 and CD81 interactions and their structural modelling in sperm prior to fertilization[J].Int J Mol Sci,2018,19(4):1236. [56] AGOPIANTZ M,XANDRE-RODRIGUEZ L,JIN B,et al.Growth arrest specific 1(Gas1) and glial cell line-derived neurotrophic factor receptor α1(Gfrα1),two mouse oocyte glycosylphosphatidylinositol-anchored proteins,are involved in fertilisation[J]. Reprod Fertil Dev,2017,29(4):824-837. [57] CLOTAIRE D Z J,DU X M,WEI Y D,et al.miR-19b-3p integrates Jak-Stat signaling pathway through Plzf to regulate self-renewal in dairy goat male germline stem cells[J].Int J Biochem Cell Biol,2018,105:104-114. [58] BAUTISTA E,ZARCO N,AGUIRRE-PINEDA N,et al.Expression of Gas1 in mouse brain:release and role in neuronal differentiation[J]. Cell Mol Neurobiol,2018,38(4):841-859. [59] PÉREZ-SÁNCHEZ G,JIMÉNEZ A,QUEZADA-RAMÍREZ M A,et al.Annexin A1,Annexin A2,and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest[J].J Cell Physiol,2018,233(5):4166-4182. [60] LUNA-ANTONIO B I,RODRIGUEZ-MUÑOZ R,NAMORADO-TONIX C,et al.Gas1 expression in parietal cells of Bowman's capsule in experimental diabetic nephropathy[J].Histochem Cell Biol,2017,148(1):33-47. [61] MOU L S,XIE N.Male infertility-related molecules involved in sperm-oocyte fusion[J].J Reprod Dev,2017,63(1):1-7. [62] ITO C,YAMATOYA K,YOSHIDA K,et al.Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion[J].Reproduction,2018,156(6):579-590. |
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